It is all about characterizing surface properties especially of particles, fillers, fibers, even minerals for flotation. IGC stands for Inverse Gas Chromatography (IGC), a method where the material with unspecified surface properties is being placed inside a GC column. But let's go step by step.
Practical examples and an amazing variety of topics!
This is already the third time we are organizing this symposium together with Adscientis, but this time the program offers so far the greatest variability, practical examples and broadest learning experiences.
Characterization of TiO2 pigments, metal-organic frameworks, minerals and porous glass surfaces
All these materials have been studied and optimized by Kronos International, Fraunhofer Institute, Helmholtz-Zentrum and University of Leipzig using pulses of gases, also known as Inverse Gas Chromatography. But how did surface energy, nanoroughness, polar interactions or Ka, Kb-values translate into better understanding of the products? The experts will share their experiences!
Surface Properties of Organic materials
For example, polysaccharides change surface properties by functionalization. And IGC is a very sensitive tool to measure it, as Dr. José Gamelas will explain. He published 2013 an excellent review about surface properties of cellulose and lignocellulosic material by IGC, see link. Difficult to measure Hansen Solubility Parameters (HSP) of excipients and liquids can be determined as a liquid layer by IGC. Dr. Eric Brendle, Adscientis, will explain the results he obtained on this topic for many pharma companies.
Inverse Liquid Chromatography - even more applied
IGC and it derived values have a very solid theoretical fundament, but sometimes the application is just in liquid phase and it is more interesting to study the behavior in-situ. Inverse Liquid Chromatography (ILC) may offer a way to study adsorption and desorption behavior under very controlled conditions, but in liquid phase and in-situ!
Dr. Matthias Kellermeier, BASF, will provide some industrial examples of ILC. The physicochemical properties of hydroxyapatite (“bone mineral”) based on ILC will be shown by Dr. Katarzyna Adamska. And for sure, some discussion will arise, where ILC might be used, too.
This IGC Symposium has a nice tradition of bringing together industrial and academic experts, foster exchange and support different approaches - with the goal to learn from each other and advance. We, the organizers, are proud to keep it this way!
Courious? Read more and register here: http://inverse-chromatography.com
Prof. Steven Abbott has an amazing way to present complex topics, like IGC, in short, 4-5 min videos.
In cooperation with Eric Brendle, Adscientis and myself, he created a nice collection of explainer videos - watch yourself:
IGC - what??? Check the video below for a super fast explanation!