Are you fully aware that many essential physicochemical properties of an Active Pharmaceutical Ingredient (API) depend on its solid-state structure? Solubility, bioavailability at desired levels, shelf-life stability, hygroscopicity, compressibility, tableting ability, electrostatic charging, plus many others, can be crucial properties. And the decision is not trivial, which kind of solid-state form should be produced or selected for an API and which data are required by patent lawyers. Sophisticated analytical tools and the right expertise are essential for successful evaluations.
Inolytix AG represents now SOLID-CHEM GmbH in Switzerland
By working together on analytical projects, it became clear that SOLID-CHEM GmbH, Bochum, Germany possesses special equipment of instruments and the right expertise – especially for the pharmaceutical industry but also for others. Customers reacted very positively, for example, “…now my favorite CRO for ssNMR….”.
Therefore, we are pleased to announce that Inolytix AG is now an exclusive partner in Switzerland for services offered by SOLID-CHEM GmbH.
Offering a comprehensive service of solid-state analysis
Exploring suitable solid-state forms (amorphous, polymorphs, salts, co-crystals, or solvates) requires a diverse methodological portfolio plus the expertise and the compounds for (co ) crystallization. Moreover, you need to precisely define all the appropriate analytical tools when matching your API with the final formulation.
Many methods exist for determining solid-state forms because the intermolecular interactions responsible for the solid-state have a very subtle character. Diffraction- and thermochemical methods, particle determination, ssNMR, humidity determination, etc. - all this requires collaborating specialists overviewing such cross-networking analyses. Finally, they have to understand the different languages when speaking to organic, bio, theoretical, and technical chemists, to pharmacists, formulation specialists, and, last but not least, with patent lawyers.
It will be our pleasure and ambitious task to provide you with the best analytical services for solid solutions for the solid-state of pharmaceutical products ranging from
• pure APIs to complement tablet formulations
• screening procedures of solid forms,
• data for patents or stability tests
Any questions about your solid product form?
Contact us, and let’s discuss it!
Please find below two supporting documents:
Inolytix, Aargau (Switzerland) - Inolytix is a startup launched in 2014 with the focus on accelerating product development and true understanding for the chemical and pharmaceutical industry. Through new and innovative analytical methods delivered by reliable and experienced partners such as SOLID-CHEM, Inolytix offers a customer-friendly service for R&D departments: providing the customer with a clear expert view and access to effective, but less known analytical methods, Inolytix manages the whole process from quotation to the industry- oriented report on the results.
Contact: Dr. Ralf Dümpelmann (for Switzerland), Founder and Managing Director
firstname.lastname@example.org, phone: +41 79 312 9327, www.inolytix.com
SOLID-CHEM GmbH (Germany, Bochum) - Founded by Prof. Boese and Dr. Schauerte as a spin-off from the University of Essen, SOLID-CHEM GmbH has become an expert center of solid solutions for the solid-state of pharmaceutical products. The philosophy is, to support customers with expert opinions based on experimental, scientific, carefully retrieved data and on precisely documented experiments. Results and reports from investigations can be potentially used for litigations, and therefore, scientific integrity is our absolute priority.
Contact: Dr. Carsten Schauerte, Managing Director and Co-founder,
email@example.com, phone: +49 234 936 90610, www.solid-chem.de